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Gilbert’s Syndrome: Symptoms, Causes, Complication, Treatment And Lifestyle

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Gilbert’s syndrome is a common, mild liver condition in which the liver doesn’t properly process a substance called bilirubin. Bilirubin is produced by the breakdown of red blood cells.

Gilbert’s syndrome is caused by an inherited gene mutation. You’re born with Gilbert’s syndrome, though it often goes undiscovered for many years. Gilbert’s syndrome is often discovered by accident, such as when you have a blood test that shows elevated bilirubin levels. Gilbert’s syndrome is also known as constitutional hepatic dysfunction and familial nonhemolytic jaundice.

Symptoms
The lone sign of Gilbert’s disease is that your skin and the whites of your eyes occasionally have a yellowish tinge (jaundice). This is caused by the slightly elevated levels of bilirubin in your blood. Some conditions and situations may increase bilirubin levels, and thereby jaundice, in people with Gilbert’s syndrome. These include:

Illness, such as a cold or the flu

Fasting or eating a very low-calorie diet

Dehydration

Menstruation

Stress

Strenuous exercise

Lack of sleep

The jaundice will go away when these conditions resolve.

Causes
Gilbert’s syndrome is caused by an abnormal gene that you inherit from your parents. The gene controls an enzyme that helps break down bilirubin in your liver. With an ineffective gene, excess amounts of bilirubin build up in your blood.

How the body normally processes bilirubin
Bilirubin is a yellowish pigment that’s made when your body breaks down old red blood cells. Bilirubin travels through your bloodstream to the liver. Normally an enzyme in liver cells breaks down the bilirubin and removes it from the bloodstream. The bilirubin passes from the liver into the intestines with bile. It’s then excreted in stool. A small amount of bilirubin remains in the blood.

How the abnormal gene is passed through families
The abnormal gene that causes Gilbert’s syndrome is common. Many people carry one copy of this abnormal gene. Two abnormal copies are usually needed to cause Gilbert’s syndrome.

Complications
Jaundice
Gilbert’s syndrome can cause episodes of jaundice. However, the jaundice is mild, goes away on its own and doesn’t cause any health problems. If jaundice persists, see your doctor.

Side effects with certain medications
The low level of the bilirubin-processing enzyme that causes Gilbert’s syndrome may also increase side effects with certain medications, since this enzyme plays a role in helping clear these medications from your body.

In particular, irinotecan (Camptosar), a cancer chemotherapy drug, can reach toxic levels if you have Gilbert’s syndrome, causing severe diarrhea. Some protease inhibitors used to treat HIV cause elevated levels of bilirubin in people with Gilbert’s syndrome.

Because of the potential for side effects, if you have Gilbert’s syndrome, talk to your doctor before taking any new medications.

Treatments
Gilbert’s syndrome doesn’t require treatment. The bilirubin levels in your blood may fluctuate over time and you may occasionally experience jaundice. But this usually goes away on its own, and it doesn’t cause any ill effects.

Lifestyle
Certain life events, such as stress, can trigger episodes of higher bilirubin levels in Gilbert’s syndrome, leading to jaundice. Doing what you can to manage those situations can help keep bilirubin under control.

These steps include:

Tell every doctor about your Gilbert’s syndrome. Gilbert’s syndrome affects the way your body processes certain medications. This has the potential to worsen side effects. Tell each doctor you visit that you have Gilbert’s syndrome, so any medications can be selected with this in mind.

Eat a healthy diet. Choose a healthy diet full of fruits and vegetables. Avoid extremely low-calorie diets. Stick to a routine eating schedule and avoid fasting or skipping meals.

Manage stress. Find ways to deal with the stresses in your life. Consider exercise or quiet time alone to cope with stress.

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Travel

Exotic Resorts May Be the Best Bet for a Holiday

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An exotic vacation usually means exploring a distant foreign country, whilst resorts are places
to go for rest, sport, or which offers a particular speciality, with many resorts being part of a
popular tourist destination or on or near a beach. If you are planning a vacation to an exotic
resort it can be a once-in-a-lifetime vacation to a far-flung destination or a luxurious place to
stay closer to home where you can enjoy some pampering.

Why stay at an exotic resort

Exotic resorts often offer all-inclusive vacation deals, along with other options that leave you
to plan your stay more precisely to your own wishes. These resorts offer excellent customer
service, superb accommodation and facilities and are usually to be found in beautiful settings.
Here are some of the best resorts from around the world for you to consider:

Four Seasons Resort, Seychelles
This famous resort has made many feel they have entered Paradise. The gentle ocean breeze
floats up the granite hillside and into your tree-house villa tucked away from the other guests
staying at the resort. This is perfect for encouraging you to relax, either by your private pool
or in the clear blue waters of Petite Anse Bay. Perfect for a romantic stay, there is a Spa for
pampering and the chance for a sunset meal on a deserted beach.

Some enjoy simply sitting on their balcony, gazing at the ocean between reading their book,
sketching or checking out international bookmakers and betting sites for the chance of a
flutter. If you want another type of adrenaline kick, check out the resorts excellent kayaking
and snorkelling facilities, which are recommended by nearly all who try it.

Anantara Resort, Hua Hin, Thailand

The ultimate tropical getaway, the Anantara Resort is an award-winning site modelled on a
traditional Thai village and is just three hours drive south of Bangkok. The location is where
Thai royalty and aristocrats have been holidaying for almost one-hundred years. Today, you
can visit historical attractions alongside theme parks and shops as well as vineyards and golf
courses.

The resort is set among 14 acres of lush tropical grounds with lotus-filled lagoons and
meandering pathways through exotic foliage, with many rooms overlooking the shoreline.
Each day, chefs prepare freshly caught local seafood alongside Thai specialities. The resort
also has an award-winning spa located within a lagoon-inspired oasis offering you the perfect
opportunity to relax.

Kurumba, Maldives

Kurumba is a well-established resort that opened almost 50 years ago and continues to offer
superb hospitality and contemporary facilities. There are seven speciality restaurants offering
cuisine from Italy to the Middle East as well as Thila, a restaurant which extends out over the
water which offers gourmet breakfasts and seafood dinners.

You can go snorkelling over the nearby reef full of colourful marine life or sign up to a dive
package as part of your stay, or just enjoy a private pool when staying at one of the spacious
villages. There are also deluxe beachfront bungalows offering direct beach access and views
of the crystal-clear waters.

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Coronavirus

Healthcare Workers To Receive Coca-Cola-Funded PPEs From Nigerian Red Cross

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Since the outbreak of the Coronavirus disease in Nigeria, our healthcare workers have continued to lead the charge against the disease. As the number of recorded COVID-19 cases in Nigeria began to increase, these healthcare workers rose to the challenge and fought tirelessly to protect the lives of Nigerians impacted by the disease.

Considering the risks these healthcare workers face, there is a crucial need for adequate protective equipment for these brave frontline workers.

Coca-Cola is excited that over 400,000 Personal Protective Equipment (PPEs) procured to support the intervention efforts of the Nigerian Government and other key stakeholders to fight the COVID 19 pandemic have arrived. We do believe that this will to provide succor to our healthcare workers on the frontlines

These PPEs comprise N95 respirators, surgical masks, examination gloves, face shields, medical gowns, no-touch thermometers, disposable aprons, heavy-duty rubber gloves, rubber boots, basic masks, disposable gloves, and hand sanitizers.

Since the first confirmed case of the disease in Nigeria reported in February, over 800 healthcare workers have contracted the disease. While Nigerians are encouraged to stay home where possible and practice social distancing, these healthcare workers are needed across the country in the continued fight against the disease.

This donation forms part of The Coca-Cola Foundation’s COVID-19 relief interventions in Nigeria. The Coca-Cola Foundation has provided $2.5m in grant to IFRC who seeks to directly impact the lives of 1.4 million people in Nigeria and across other countries in West and Central Africa under this partnership.

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Events in Nigeria

Taking Care of Tomorrow’s Leaders Today – The itel, Lagos Food Bank Example

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Waking up to a special meal or choice gift is the best feeling ever. Hundreds of children in Mushin, mainland Lagos, had a filling taste of this feeling for the October 1 st celebrations. It’s an experience they will remember for a long time.

Being one of the most responsible corporate citizens around, celebrating Independence Day was always going to be on the radar for itel Mobile. To make this possible and memorable, the brand got to work in earnest. The focus of the work was picking the best way to commemorate the 60th independence anniversary of the most populous black nation on earth.

The efforts soon paid off through an impact-driven partnership with the Lagos Food Bank Initiative. With the arrangement, both partners considered a couple of activities capable of affecting communities positively and bringing smiles to people’s faces in Lagos. At the end of the exercise, taking care of children, the leaders of tomorrow, in the commercial city secured the highest votes.

With the decision, itel Mobile set about making this happen. Not surprisingly, the decision was
influenced by giving children the means to excel and prepare them for leadership and nation-building, for them to enjoy better life. For the good of their immediate family, community and the Nigerian society.

Idiko, Mushin, a suburb of mainland Lagos, was chosen as the benefiting community. And the partners strategically reached out to the beneficiaries, children and families, with gifts of love, care, happiness and support made possible by the itel Love Always On CSR initiative.

Over 1,000 families benefited from the gesture as well as 600 children, and each one of them received food packages to celebrate Nigeria’s 60 th Independence Day commemoration.

Speaking on the event and itel’s Love Always On CSR Initiative, Oke Umurhohwo, itel’s Marketing Manager said, ‘We wanted to mark this year’s Independence Day celebrations differently, and that is why we did something so momentous for our children. Children are the backbone of any longstanding community, and as such, we are proud to be able to give back and support them on their journey as leaders of tomorrow and for a better life.’

To meet the demands of the memorable event, 30 volunteers joined the customer-centric brand and the Lagos-based NGO to share smiles, and to convey just how important it is to love and take care of today’s children who will ultimately become leaders of tomorrow.

With the thoughtful activity, there are insights for everyone, from the government to citizens, on partnerships that are capable of making life better for children. Indeed, itel Mobile and the Lagos Food Bank Initiative have offered a great template on bringing this to reality.

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