Connect with us

News Feed

BREAKTHROUGH: Blindness Can Be Cured

Published

on

The prospect of reversing blindness has made a significant leap, according to scientists in the UK.

tanya-vlach

An animal study in the journal Nature Biotechnology showed the part of the eye which actually detects light can be repaired using stem cells.

The team at Moorfields Eye Hospital and University College London say human trials are now, for the first time, a realistic prospect.

Experts described it as a “significant breakthrough” and “huge leap” forward.

Photoreceptors are the cells in the retina which react to light and convert it into an electrical signal which can be sent to the brain.

However, these cells can die off in some causes of blindness such as Stargardt’s disease and age-related macular degeneration.

There are already trials in people to use stem cells to replace the “support” cells in the eye which keep the photoreceptors alive.

Blind mice

Now the London-based team have shown it is possible to replace the light-sensing cells themselves, raising the prospect of reversing blindness.

They have used a new technique for building retinas in the laboratory. It was used to collect thousands of stem cells, which were primed to transform into photoreceptors, and injected them into the eyes of blind mice.

The study showed that these cells could hook up with the existing architecture of the eye and begin to function.

However, the effectiveness is still low. Only about 1,000 cells out of a transplant of 200,000 actually hooked up with the rest of the eye.

Lead researcher Prof Robin Ali said: “This is a real proof of concept that photoreceptors can be transplanted from an embryonic stem cells source and it give us a route map to now do this in humans.

“That’s why we’re so excited, five years is a now a realistic aim for starting a clinical trial.”

_68841687_p4240081-false-colour_sem_of_rods_and_cones_of_the_retina-spl

Rods and cones Rods, blue, and cones, blue-green, detect light and create electrical signals which are sent to the brain

The eye is one of the most advanced fields for stem cell research.

It is relatively simple as the light sensing cells only have to pass their electrical message on to one more cell in order to get their message to the brain, unlike an attempt to reverse dementia which would require cells to hook up with far more cells all across the brain.

The immune system is also very weak in the eye so there is a low chance of the transplant being rejected. A few cells can also make a big difference in the eye.

Tens of thousands of stem cells in the eye could improve vision, but that number of stem cells would not regenerate a much larger organ such as a failing liver.

Prof Chris Mason, from University College London, told the BBC: “I think they have made a major step forward here, but the efficiency is still too low for clinical uses.

“At the moment the numbers of tiny and it will take quite a bit of work to get the numbers up and then the next question is “Can you do it in man?”

“But I think it is a significant breakthrough which may lead to cell therapies and will give a much expanded knowledge on how to cure blindness.”

Dr Marcelo Rivolta, from the University of Sheffield, said the study was a “huge leap” forward for treating blindness and could have implications across stem cell research.

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

News Feed

Offa Polytechnic Student Union Government Gives Merit Award To Cultist Groups

Published

on

Offa State Polytechnic student union government gives merit award to cultist groups in the school.

According to a Twitter user, Ifemosu Michael wrote;

“When you think you have seen it all… Student Union Government of Offa Polytechnic gave merit Awards to Secret Cults in the school. Hey Lawd!!!”

Continue Reading

News Feed

Man Excited As Davido Gifts Him 1M After Making A Video On His Birthday

Published

on

Man gets excited as Davido gifts him 1M after making a video on his birthday.

Taking to his Twitter handle to share the gist, DJ Peejay wrote;

“DAVIDO JUST SENT ME 1 MILLION cos of the video I made on his birthday”

Watch the video below;

Continue Reading

News Feed

Water tank driver accuses Duncan Mighty of assaulting him in Rivers

Published

on

 

Self-acclaimed Port Harcourt First Son, Duncan Mighty is currently trending on social media for the wrong reasons.

A water tank driver, Okabam John has accused singer, Duncan Mighty of assaulting him in Port Harcourt, Rivers state.

It was gathered that the incident reportedly happened on Saturday, November 21, 2020 at about 9:40am when the driver was on duty.

Narrating his ordeal to some Civil Rights Activists on Tuesday November 24, after he was allegedly discharged from the hospital, John, a native of Elele Town in Ikwerre Local Government Area of the state and an employee of Julius Berger Nigeria Limited, claimed that the musician struck him on the head with a traditional staff made of elephant tusk.

According to the driver, while on duty a private car was parked close to his water filling spot. He tried notifying the driver who refused to wind down. He reportedly bent his head to talk to the driver only to discover it was Duncan Mighty.

John said that before he could speak, the singer allegedly struck his head using a traditional staff. He said the second strike was blocked with his hand. He claimed that he could not see when the singer drove off as his eyes were covered with blood.

Confirming the incident on Tuesday, one Ndubueze Obodowhuo, accused Duncan Mighty of using his VIP status to intimidate his people. He also shared a ‘medical report’ stating that John was treated for “shoulder dislocation and scalp laceration.”

Mr John is now calling on his employer, the management of Julius Berger, Security Agencies and Human Rights Organisations to help him get justice. His post below:

“This is Mr. OKABAM JOHN a native of Elele town in Ikwerre LGA of Rivers State, he’s currently employed by JULIUS BERGER NIG.PLC in Port Harcourt and his service engagement is within Judges quarters elelenwo-street, GRA Port Harcourt.

“According to Mr. OKABAM JOHN a Water-tank driver with Julius Berger, Tanker number – B8751, On Saturday 21st of November 2020 at about 9:40am while he was on duty. A private car was parked close to his water filling spot, he tried notifying the driver who refused to wine down, he bent his head to talk with the driver surprisingly, it was Duncan mighty.

“Before he could explain, his head was struck by Duncan mighty using a traditional staff(Elephant tusk), the second strike was blocked with his hand. He(Okabam John) didn’t see how the artist drove off because, blood covered his eyes at that moment.

“Mr. Okabam John narrated this incident after being discharged from the hospital. Duncan doesn’t show up when he’s publicly needed, rather he uses his VIP influence to undo his people. Celebrities should be celebrated by their positivity, their influence shouldn’t pose danger to the society rather it should serve as liberation to the people.

“Mr. OKABAM JOHN is calling on the management of Julius Berger, Security Agents and Human Rights Organisations for justice to be done in his case, to avoid a re-occurance.”

Continue Reading

Trending